Infusion billing services for infusion centers and in-office infusion suites

Infusion billing for physician practices and ambulatory infusion centers: biologics, immune globulin, iron, hydration and injections, with administration coded from documented start and stop times, drugs billed by the unit, and authorizations and site-of-care rules handled before the first dose.

IV bag hanging from a stainless steel infusion stand
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Infusion billing, from the chair to the paid claim

Infusion billing is two claims in one: the drug and the time it took to give it. The administration is coded from the start and stop times in the record, each drug is billed in its HCPCS unit with its waste reported, authorizations are approved before the patient sits down, and any denial is worked until it is paid.

$330M

in improper Medicare payments for Part B drugs other than chemotherapy in CMS’s 2025 review

80.0%

of those drug errors were missing or insufficient documentation

An infusion visit can involve several drugs, a hydration line and a push, and only one of them is the initial service. Each later one is billed as sequential, concurrent or an additional hour, and each depends on the minutes in the record. The drugs themselves cost far more than the administration, so a wrong unit count or missing authorization can turn one visit into a large write-off.

The times and the units decide the claim. That is why we rebuild every infusion visit from the documented times and doses before the claim goes out.

Administration, drugs and authorizations

Every infusion claim has an administration part, a drug part and a coverage part. Each one can be wrong on its own. Here is what goes wrong in each, and what we do.

Administration time

Pays forInfusions, pushes, injections and hydration, coded by the order and length of each one.

Where it breaks

What we do

Drugs and units

Pays forBiologics, immune globulin, iron and other drugs, billed in their HCPCS unit sizes.

Where it breaks

What we do

Coverage and site of care

Pays forAuthorizations, reauthorizations and the plan’s rules on where an infusion may be given.

Where it breaks

What we do

Coding infusion time: initial, sequential, concurrent and add-on

A therapeutic infusion is billed with 96365 for the first hour and 96366 for each additional hour, which is billed only when the infusion runs more than 30 minutes past the previous hour. An infusion of 15 minutes or less is reported as an IV push (96374). Hydration follows the same pattern with 96360 and 96361, but needs more than 30 minutes to be billed at all.

Only one initial service is billed per encounter. In a physician office it is the service that is the main reason for the visit. Each new drug after it is a sequential infusion (96367) or push (96375), and a drug infused at the same time as another is billed once as concurrent (96368). The record needs the start and stop time of each line for any of this to hold.

What we do: we lay out each visit’s lines in order from the documented times, pick the initial service, code the rest as sequential, concurrent or additional hours, and check each against its time threshold before the claim goes out.

IV bag and infusion pump set up beside a hospital bed
Infusion visit billing checklist

Before you bill

  1. Lines: every infusion, push, injection and hydration given
  2. Times: the start and stop time of each one
  3. Drugs: each drug, dose and vial size, and who supplied it
  4. Authorization: the approved drug, dose count and dates

What goes on the claim

  1. Initial: one initial service per encounter
  2. After it: 96367 or 96375 for each new drug, 96368 once for a concurrent drug
  3. Extra hours: 96366 or 96361 only past 30 minutes beyond the hour
  4. Drug lines: HCPCS units, with JZ or a JW line on single-dose vials
Sources: CPT drug administration guidelines; Medicare Claims Processing Manual, chapter 12, section 30.5 (drug administration); CMS JW and JZ Modifier FAQs; CMS, 2025 Medicare Fee-for-Service Supplemental Improper Payment Data.

Administration and drug codes for infusion services

An infusion claim pairs time-based administration codes with drug codes in fixed units. These are the codes we see most, with what payers check on each.

Infusion codes and what payers look for
CodeWhat it coversWhat payers look for
9636596366Therapeutic infusion, first hour and each additional hourMore than 15 minutes for 96365; more than 30 minutes past the hour for 96366.
9636796368Sequential and concurrent infusionA new drug after the initial service; concurrent billed once per encounter.
9636096361Hydration, first hour and each additional hourMore than 30 minutes, and a documented reason for the fluids.
9637496375IV push, initial and each sequential new drug15 minutes or less, or a push by definition.
96372Subcutaneous or intramuscular injectionNot billed with an infusion of the same drug.
J1569Immune globulin (Gammagard Liquid), per 500 mgUnits from the dose, and the diagnosis the plan covers.
J2350J2323J3380Ocrelizumab, natalizumab and vedolizumab, per 1 mgAuthorization, units from the dose, and JZ or JW.
J1745Infliximab, per 10 mgThe plan's preferred product and units from the weight-based dose.

Modifiers that decide the claim

JZ

No drug discarded

Required by Medicare on single-dose drugs when the whole dose was given.

JW

Drug discarded

The unused part of a single-dose vial, billed on its own line.

59 / XU

Separate IV site

A second initial service when a separate access site was medically needed. Our modifier 59 guide

25

Separate visit

A visit significant and separate from the infusion. Modifier 25 explained

GZ

No ABN on file

Medicare: a drug expected to be denied, with no signed notice.

GA

ABN on file

Medicare: a drug or service that may not be covered, with a signed notice.

Sources: Medicare Claims Processing Manual, chapter 12, section 30.5, and chapter 17 (drugs and biologicals); CMS JW and JZ Modifier FAQs. CPT is a registered trademark of the American Medical Association; the descriptions above are summaries. Reviewed October 2026.

When an infusion practice should hand off its billing

It is not for every practice. If you are a hospital-employed group whose billing the hospital handles, you do not need us. And if your in-house team keeps denials low and receivables current, keep them, and consider a periodic billing audit instead.

How we take over your billing

  1. Free account review

    We look at your clean-claim rate, your denials by payer and reason, administration coding from documented times, drug units and waste, authorizations, and your aging receivables, and tell you what we find, whether or not you go further with us.

  2. Onboarding

    We get access to your practice management system and clearinghouse, load each payer's authorization and bundling rules and your fee schedules, list active infusion patients, their drugs and authorizations, and agree how escalations work. Most practices are live within one to two weeks.

  3. Daily billing

    Infusions, pushes and drugs are coded and claims submitted within 24 hours. Rejections are corrected the same day, remittances posted as they arrive, times, units and authorizations checked, and denials worked to their cause, all inside your system.

  4. Monthly reporting

    A report you can read in ten minutes: what was billed and collected by payer, site and service line, what was denied and why, authorizations pending, and what is aging.

We work with your software

You do not change systems to work with Summit Billing Solutions. We work in the practice management and EHR systems below, and through the clearinghouse you already use. If your EHR is not shown, ask; the list grows as we onboard practices.

athenahealth EHR and revenue cycle management software logo
eClinicalWorks EHR software logo
NextGen Healthcare EHR software logo
Allscripts EHR software logo
HealthFusion MediTouch EHR software logo
CureMD EHR and practice management software logo
AdvancedMD practice management and medical billing software logo
Tebra practice management and medical billing software logo
Availity clearinghouse logo
Office Ally clearinghouse and practice management software logo

Infusion billing with Summit Billing Solutions

Each visit rebuilt from its times and doses

Before an infusion claim goes out, we order each line by its documented times, pick the initial service, and convert every dose into units with its waste reported.

A named contact and a weekly call

You know who is working your account, and you hear from them every week. A familiar face, not a ticket queue.

Month to month, no long-term lock-in

If we are not earning the relationship, you can leave. That keeps us honest.

Headquartered in New Hampshire, serving all 50 states

Summit is a US company based in Salem, New Hampshire, billing for practices nationwide with the state-by-state payer and Medicaid knowledge that takes.

Results and reviews

95-98%

First-pass claim rate

24 hrs

Claims submitted within

28

Average days in A/R

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Infusion billing costs

Drug charges make infusion claims some of the largest a practice sends, so accuracy on each one matters more than volume. A fee that is a share of collections ties our pay to getting those claims paid as billed.

Summit Billing Solutions charges between 3% and 9% of monthly collections. Your rate depends on infusion volume, the drugs you buy and bill, how many need authorization, and the state of the receivables, which we see in the free account review.

3% to 9%

of monthly collections

Other specialties we bill for

We bill for more than 40 specialties, for practices in all 50 states, from Salem, New Hampshire. Each one has its own codes, modifiers and payer rules.

Infusion billing questions we hear most

Most billing companies charge a percentage of collections, and a few charge a flat monthly or per-claim fee. Summit Billing Solutions charges between 3% and 9% of monthly collections. For an infusion practice or center, the rate depends on infusion volume, the drugs you buy and bill, authorization volume and the state of your receivables, and we quote your exact rate after the free account review.

Get your infusion times and units checked

A free account review looks at your clean-claim rate, your denials by payer and reason, administration coding from documented times, drug units and waste, and authorizations, and your aging receivables, and tells you what we would change. No cost, no obligation, and no pressure to continue. What the review covers, step by step, is on the free account review page.

50A Northwestern Dr Ste 3, Salem, NH 03079-4827

603-207-3172

(866) 906-3116

info@summitbillingsolutions.com

Mon - Fri @ 9am - 5pm